• BS, Biology, California Institute of Technology, 1999
• Ph D, Neuroscience, Brandeis University, 2004

Journal Articles

D F Brockway, K R Griffith, C M Aloimonos, T T Clarity, J B Moyer, Gary Smith, N C Dao, Md Hossain, Patrick Drew, J A Gordon, D A Kupferschmidt and Nicole Crowley, 2023, "Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior.", Cell reports, 42, (8), pp. 112976

K W Gheres, H S Ünsal, X Han, Qingguang Zhang, K L Turner, Nanyin Zhang and Patrick Drew, 2023, "Arousal state transitions occlude sensory-evoked neurovascular coupling in neonatal mice.", Communications biology, 6, (1), pp. 738

T T Vo, G H Im, K Han, M Suh, Patrick Drew and S G Kim, 2023, "Parvalbumin interneuron activity drives fast inhibition-induced vasoconstriction followed by slow substance P-mediated vasodilation.", Proceedings of the National Academy of Sciences of the United States of America, 120, (18), pp. e2220777120

Qingguang Zhang, S R Cramer, K L Turner, Thomas Neuberger, Patrick Drew and Nanyin Zhang, 2023, "High-frequency neuronal signal better explains multi-phase BOLD response.", NeuroImage, 268, pp. 119887

K L Turner, K W Gheres and Patrick Drew, 2023, "Relating Pupil Diameter and Blinking to Cortical Activity and Hemodynamics across Arousal States.", The Journal of neuroscience : the official journal of the Society for Neuroscience, 43, (6), pp. 949-964

K L Turner, K W Gheres and Patrick Drew, 2022, "Relating pupil diameter and blinking to cortical activity and hemodynamics across arousal states.", The Journal of neuroscience : the official journal of the Society for Neuroscience

Qingguang Zhang, S R Cramer, Ziguang Ma, K L Turner, K W Gheres, Yunting Liu, Patrick Drew and Nanyin Zhang, 2022, "Brain-wide ongoing activity is responsible for significant cross-trial BOLD variability.", Cerebral cortex (New York, N.Y. : 1991), 32, (23), pp. 5311-5329

Patrick Drew, 2022, "Neurovascular coupling: motive unknown", Trends in Neurosciences, 45, (11), pp. 809-819

S Mirg, K L Turner, Huan Chen, Patrick Drew and Sri-Rajasekhar Kothapalli, 2022, "Photoacoustic imaging for microcirculation.", Microcirculation (New York, N.Y. : 1994), 29, (6-7), pp. e12776

W D Haselden, Patrick Drew and Ephraim W. Church, 2022, "Lessons for the pathogenesis of vasospasm from a patient with sickle cell disease, moyamoya disease, subarachnoid hemorrhage, and 1 month of persistent vasospasm: illustrative case.", Journal of neurosurgery. Case lessons, 4, (1), pp. CASE2290

Qingguang Zhang, W D Haselden, S Charpak and Patrick Drew, 2022, "Could respiration-driven blood oxygen changes modulate neural activity?", Pflugers Archiv : European journal of physiology

Yuan-Ting Wu, H C Bennett, U Chon, D J Vanselow, Qingguang Zhang, R Muñoz-Castañeda, Keith C Cheng, P Osten, Patrick Drew and Yongsoo Kim, 2022, "Quantitative relationship between cerebrovascular network and neuronal cell types in mice.", Cell reports, 39, (12), pp. 110978

R T Kedarasetti, Patrick Drew and Francesco Costanzo, 2022, "Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model.", Fluids and barriers of the CNS, 19, (1), pp. 34

Qingguang Zhang, K L Turner, K W Gheres, Md Hossain and Patrick Drew, 2022, "Behavioral and physiological monitoring for awake neurovascular coupling experiments: a how-to guide.", Neurophotonics, 9, (2), pp. 021905

S Mirg, Huan Chen, K L Turner, K W Gheres, Jude Liu, Bruce Gluckman, Patrick Drew and Sri-Rajasekhar Kothapalli, 2022, "Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window.", Optics letters, 47, (5), pp. 1121-1124

Qingguang Zhang, K W Gheres and Patrick Drew, 2021, "Origins of 1/f-like tissue oxygenation fluctuations in the murine cortex.", PLoS biology, 19, (7), pp. e3001298

A K Aydin, W D Haselden, J Dang, Patrick Drew, S Charpak and D Boido, 2021, "Iliski, a software for robust calculation of transfer functions.", PLoS computational biology, 17, (6), pp. e1008614

A Das, K Murphy and Patrick Drew, 2021, "Rude mechanicals in brain haemodynamics: non-neural actors that influence blood flow.", Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 376, (1815), pp. 20190635

K L Turner, K W Gheres, Elizabeth Anne Proctor and Patrick Drew, 2020, "Neurovascular coupling and bilateral connectivity during NREM and REM sleep.", eLife, 9

C T Echagarruga, K W Gheres, J N Norwood and Patrick Drew, 2020, "nNOS-expressing interneurons control basal and behaviorally evoked arterial dilation in somatosensory cortex of mice.", eLife, 9

Patrick Drew, C Mateo, K L Turner, X Yu and D Kleinfeld, 2020, "Ultra-slow Oscillations in fMRI and Resting-State Connectivity: Neuronal and Vascular Contributions and Technical Confounds.", Neuron, 107, (5), pp. 782-804

R T Kedarasetti, K L Turner, C Echagarruga, Bruce Gluckman, Patrick Drew and Francesco Costanzo, 2020, "Functional hyperemia drives fluid exchange in the paravascular space.", Fluids and barriers of the CNS, 17, (1), pp. 52

W D Haselden, R T Kedarasetti and Patrick Drew, 2020, "Spatial and temporal patterns of nitric oxide diffusion and degradation drive emergent cerebrovascular dynamics.", PLoS computational biology, 16, (7), pp. e1008069

R T Kedarasetti, Patrick Drew and Francesco Costanzo, 2020, "Arterial pulsations drive oscillatory flow of CSF but not directional pumping.", Scientific reports, 10, (1), pp. 10102

A K Aydin, W D Haselden, Y Goulam Houssen, C Pouzat, R L Rungta, C Demené, M Tanter, Patrick Drew, S Charpak and D Boido, 2020, "Transfer functions linking neural calcium to single voxel functional ultrasound signal.", Nature communications, 11, (1), pp. 2954

Q Zhang, M Roche, K W Gheres, E Chaigneau, R T Kedarasetti, W D Haselden, S Charpak and Patrick Drew, 2019, "Cerebral oxygenation during locomotion is modulated by respiration.", Nature communications, 10, (1), pp. 5515

Patrick Drew, A T Winder and Qiming Zhang, 2019, "Twitches, Blinks, and Fidgets: Important Generators of Ongoing Neural Activity.", The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 25, (4), pp. 298-313

Patrick Drew, 2019, "Vascular and neural basis of the BOLD signal.", Current opinion in neurobiology, 58, pp. 61-69

J N Norwood, Q Zhang, D Card, A Craine, Timothy M Ryan and Patrick Drew, 2019, "Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate.", eLife

Matthew Adams, A T Winder, P Blinder and Patrick Drew, 2018, "The pial vasculature of the mouse develops according to a sensory-independent program.", Scientific reports, 8, (1), pp. 9860

Paddy Ssentongo, Anna E. Robuccio, Godfrey Thuku, Derek G Sim, Ali Nabi, Fatemeh Bahari, Balaji Shanmugasundaram, Myles W. Billard, Andrew Geronimo, Kurt W. Short, Patrick Drew, Jennifer Baccon, Steven L. Weinstein, Frank G. Gilliam, Jose A. Stoute, Vernon M. Chinchilli, Andrew F Read, Bruce Gluckman and Steven Schiff, 2017, "A Murine Model to Study Epilepsy and SUDEP Induced by Malaria Infection", SCIENTIFIC REPORTS, 7

Yu-Rong Gao, Yuncong Ma, Qingguang Zhang, Aaron T. Winder, Zhifeng Liang, Lilith Antinori, Patrick Drew and Nanyin Zhang, 2017, "Time to wake up: Studying neurovascular coupling and brain-wide circuit function in the un-anesthetized animal", NEUROIMAGE, 153, pp. 382-398

Aaron T. Winder, Christina Echagarruga, Qingguang Zhang and Patrick Drew, 2017, "Weak correlations between hemodynamic signals and ongoing neural activity during the resting state", Nature Neuroscience, 20, (12), pp. 1761-1769

Y R Gao and Patrick Drew, 2016, "Effects of Voluntary Locomotion and Calcitonin Gene-Related Peptide on the Dynamics of Single Dural Vessels in Awake Mice.", The Journal of neuroscience : the official journal of the Society for Neuroscience, 36, (8), pp. 2503-16

B X Huo, S E Greene and Patrick Drew, 2015, "Venous cerebral blood volume increase during voluntary locomotion reflects cardiovascular changes.", NeuroImage, 118, pp. 301-12

Y R Gao, S E Greene and Patrick Drew, 2015, "Mechanical restriction of intracortical vessel dilation by brain tissue sculpts the hemodynamic response.", NeuroImage, 115, pp. 162-76

M J Shirey, J B Smith, S E Greene, B X Huo and Patrick Drew, 2015, "Brief anesthesia, but not voluntary locomotion, significantly alters cortical temperature.", Journal of neurophysiology, 114, (1), pp. 309-22

A Y Shih, C Rühlmann, P Blinder, A Devor, Patrick Drew, B Friedman, P M Knutsen, P D Lyden, C Matéo, L Mellander, N Nishimura, C B Schaffer, P S Tsai and D Kleinfeld, 2015, "Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture.", Microcirculation (New York, N.Y. : 1994), 22, (3), pp. 204-18

Bing-Xing Huo, Yu-Rong Gao and Patrick Drew, 2015, "Quantitative separation of arterial and venous cerebral blood volume increases during voluntary locomotion.", NeuroImage, 105, pp. 369-79

A Letourneur, V Chen, G Waterman and Patrick Drew, 2014, "A method for longitudinal, transcranial imaging of blood flow and remodeling of the cerebral vasculature in postnatal mice", Physiological Reports, 2, (12), pp. 10

Yu-Rong Gao and Patrick Drew, 2014, "Determination of vessel cross-sectional area by thresholding in Radon space.", Journal of Cerebral Blood Flow and Metabolism, 34, pp. 1180-1187

Bing-Xing Huo, Jared B Smith and Patrick Drew, 2014, "Neurovascular Coupling and Decoupling in the Cortex during Voluntary Locomotion.", Journal of Neuroscience, 34, (33), pp. 10975-81

Jonathan D Driscoll, Andy Y Shih, Patrick Drew, Gert Cauwenberghs and David Kleinfeld, 2013, "Two-photon imaging of blood flow in the rat cortex.", Cold Spring Harb Protoc, 8, pp. 759-67

Andy Y Shih, Celine Mateo, Patrick Drew, Philbert S Tsai and David Kleinfeld, 2012, "A polished and reinforced thinned-skull window for long-term imaging of the mouse brain.", JoVE, 61

A Y Shih, J D Driscoll, P J Drew, N Nishimura, C B Schaffer and D Kleinfeld, 2012, "Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain", J Cereb Blood Flow Metab, 32, (7), pp. 277-309

David Kleinfeld, Pablo Blinder, Patrick Drew, Jonathan D Driscoll, Arnaud Muller, Philbert S Tsai and Andy Y Shih, 2011, "A guide to delineate the logic of neurovascular signaling in the brain.", Frontiers in Neuroenergetics, 3, (1), pp. 9

Patrick Drew, Andy Y Shih and David Kleinfeld, 2011, "Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity.", Proceedings of the National Acadamy of Sciences, 108, (20), pp. 8473-8478

Patrick Drew, Andy Y Shih, Jonathan D Driscoll, Per Magne Knutsen, Pablo Blinder, Dimitrios Davalos, Katerina Akassoglou, Philbert S Tsai and David Kleinfeld, 2010, "Chronic optical access through a polished and reinforced thinned skull.", Nature Methods, 7, (12), pp. 981-984

Patrick Drew, Pablo Blinder, Gert Cauwenberghs, Andy Y Shih and David Kleinfeld, 2010, "Rapid determination of particle velocity from space-time images using the Radon transform.", Journal of Computational Neuroscience, 29, (1-2), pp. 5-11

Andy Y Shih, Beth Friedman, Patrick Drew, Philbert S Tsai, Patrick D Lyden and David Kleinfeld, 2009, "Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke.", Journal of Cerebral Blood Flow and Metabolism, 29, (4), pp. 738-51

Philbert S Tsai, John P Kaufhold, Pablo Blinder, Beth Friedman, Patrick Drew, Harvey J Karten, Patrick D Lyden and David Kleinfeld, 2009, "Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels.", Journal of Neuroscience, 29, (46), pp. 14553-70

Lu Li, Kevin J Bender, Patrick Drew, Shantanu P Jadhav, Emily Sylwestrak and Daniel E Feldman, 2009, "Endocannabinoid signaling is required for development and critical period plasticity of the whisker map in somatosensory cortex.", Neuron, 64, (4)

Patrick Drew and Daniel E Feldman, 2009, "Intrinsic signal imaging of deprivation-induced contraction of whisker representations in rat somatosensory cortex.", Cerebral Cortex, 19, (2), pp. 331-48

Patrick Drew, Jeff H Duyn, Eugene Golanov and David Kleinfeld, 2008, "Finding coherence in spontaneous oscillations.", Nature Neuroscience, 11, (9)

Jason Wolfe, Dan N Hill, Sohrab Pahlavan, Patrick Drew, David Kleinfeld and Daniel E Feldman, 2008, "Texture coding in the rat whisker system: slip-stick versus differential resonance.", PLOS Biology, 6, (8), pp. e215

Patrick Drew and Daniel E Feldman, 2007, "Representation of moving wavefronts of whisker deflection in rat somatosensory cortex.", Journal of Neurophysiology, 98, (3), pp. 1566-80

P J Drew and L F Abbott, 2006, "Extending the effects of spike-timing-dependent plasticity to behavioral timescales", Proceedings of the National Acadamy of Sciences, 103, (23), pp. 8876-81

P J Drew and L F Abbott, 2006, "Models and properties of power-law adaptation in neural systems", Journal of Neurophysiology, 96, (2), pp. 826-81

S Fusi, P J Drew and LF Abbott, 2005, "Cascade models of synaptically stored memories", Neuron, 45, (2), pp. 2697-706

P J Drew and L F Abbott, 2003, "Model of song selectivity and sequence generation in area HVc of the songbird", Joournal of Neurophysiology, 89, (5), pp. 2697-2706

Patrick Drew, R Sayres, K Watanabe and S Shimojo, 2001, "Pupillary response to chromatic flicker", Experimental Brain Research, (136), pp. 256-62

Qingguang Zhang, Kevin Turner, Kyle Gheres, Md Shakhawat Hossain and Patrick Drew, , ": Behavioral and physiological monitoring for awake neurovascular coupling experiments: A how-to guide"

Conference Proceedings

Kurt W. Short, Ephraim W. Church, Akshal S. Patel, Kevin M. Cockroft and Patrick Drew, 2016, "Absence of Cortical Microvessel Spasm During Large Vessel Spasm Following Experimental Subarachnoid Hemorrhage", STROKE, 47

Abstracts

Qingguang Zhang, Kyle Gheres and Patrick Drew, 2017, "Noradrenergic modulation of neurovascular coupling in awake behaving mice"

Qingguang Zhang, Kyle Gheres and Patrick Drew, 2017, "Neuronal and non-neuronal factors mediate behavioral-state dependent development of functional hyperemia in the somatosensory cortex of juvenile mice"

Priankshesh Patki, Bruce Gluckman, Francesco Costanzo and Patrick Drew, 2017, "Mixture theory based analysis of the glymphatic system"

Other

H Chen, S Mirg, P Gaddale, Shailaja Agrawal, M Li, V Nguyen, T Xu, Q Li, Jude Liu, W Tu, X Liu, Patrick Drew, Nanyin Zhang, Bruce Gluckman and Sri-Rajasekhar Kothapalli, 2023, "Dissecting Multiparametric Cerebral Hemodynamics using Integrated Ultrafast Ultrasound and Multispectral Photoacoustic Imaging.", bioRxiv : the preprint server for biology

H C Bennett, Qingguang Zhang, Yuan-Ting Wu, U Chon, H J Pi, Patrick Drew and Yongsoo Kim, 2023, "Aging drives cerebrovascular network remodeling and functional changes in the mouse brain.", bioRxiv : the preprint server for biology

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